Search on: INITIATION FACTOR-5, EUKARYOTIC 
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Descriptor English:   Eukaryotic Initiation Factor-5 
Descriptor Spanish:   Factor 5 Eucariótico de Iniciación 
Descriptor Portuguese:   Fator de Iniciação 5 em Eucariotos 
Synonyms English:   Eukaryotic Peptide Initiation Factor-5
Eukaryotic Initiation Factor 5
Eukaryotic Peptide Initiation Factor 5
Initiation Factor-5, Eukaryotic
Peptide Initiation Factor EIF 5
EIF-5
Peptide Initiation Factor EIF-5  
Tree Number:   D12.644.360.325.150.300
D12.776.476.325.150.300
D12.776.835.725.868.750
Definition English:   A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the hydrolysis of the bound GTP. The hydrolysis of GTP causes the release of EUKARYOTIC INITIATION FACTOR-2 and EUKARYOTIC INITIATION FACTOR-3 from the 40S subunit and the subsequent joining of the 60S ribosomal subunit to the 40S complex to form the functional 80S initiation complex 
Pharmacological Action:   GTP Phosphohydrolase Activators
 
History Note English:   2003; use EUKARYOTIC INITIATION FACTOR-5 (NM) 1982-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   37453 
Unique Identifier:   D040061 

Occurrence in VHL:
 

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